University School of Medicine researchers, with the help of
University of Toronto researchers, are looking at using animal models
of gonorrhea to come up with a vaccine that would prevent the STD
it couldn’t be at a better time with the increasing concern of
cases of antibiotic resistance in gonorrhea infections.
study looks at how the infection advances and determine how efficient
the next generation of vaccines will be. A mouse model may not
accurately portray the infection’s severity and the various kinds
of human immune responses.
2017, there have been over 550,000 new gonorrhea cases reported to
the CDC – an increase of 67 percent since 2013. The World Health
Organization said there are more than 106.1 million new cases each
year of the STD. However, researchers believe the number could be
even higher with many cases going unreported.
top of that, reports show that there have been numerous cases of
antibiotic-resistant gonorrhea, which makes it even more imperative
to develop new gonorrhea vaccines that can tackle the sexually
transmitted disease and use relevant animal models to test the
Dr. Lee M. Wetzler said using infectious diseases’ models to study pathogens and possible vaccine development is riddled with problems with many of the human-specific pathogens changing mechanisms of infection. It’s imperative, when using models, to ensure the infections are fully looked into to determine it would mimic the same reaction in humans as they do in animals.