4 Possible Treatment Options for Chancroid STD Bacteria

January 27, 2019
by John Kelly, MD
4 Possible Treatment Options for Chancroid STD Bacteria

Sexually transmitted disease Chancroid is caused by the Haemophilus ducreyi, a small bacteria that can lead to genital ulceration syndrome. This syndrome can also cause bubo formation and lymph nodes inflammation.

Diagnosis for chancroid isn’t fast or sensitive, but a doctor should begin treatment right away if they suspect their patient has the disease. Many people are unaware of this STD or that it could be a potential factor for HIV transmission (human immunodeficiency virus).

The Centers for Disease Control and Prevention said chancroid’s treatment could entail four different types of treatment:

  • 1 intramuscular dose 250mg of ceftriaxone
  • 1 dose of azithromycin
  • 3 days of 500mg oral ciprofloxacin (two times a day)
  • 7 days of 500mg oral erythromycin (three times a day)

Both ceftriaxone and azithromycin have an advantage because they are single dosage prescription, but the other methods are necessary for people who have HIV. Ciprofloxacin should not be prescribed to women pregnant or lactating as well anyone under the age of 18. If treatment is successful, there will be less tenderness, no purulence with some remnants of ulcers after the initial treatment. Uncircumcised men and people with HIV may have slower healing times.

The World Health Organization has suggested a broad syndromic approach to treating genital ulcers. This kind of management is offered to areas where there is little to no lab support, and treatment is founded on the local epidemiological patterns and those with antibiotic sensitivity.

The key premise to the syndromic approach is to treat suffers during the first visit using various antimicrobials and cover the probable etiological infectious agents around the area. It doesn’t eliminate the need for lab work.

The approach has garnered more success than trusting algorithms and clinical diagnosis. It’s also been used in certain countries of sub-Saharan Africa.

What Efforts Are Being Made To Prevent A Chancroid Outbreak?

In an effort to keep an outbreak of chancroid from occurring, there have been numerous interventions developed that target commercial sex workers, reasonable syndromic management of the ulcers and peer interventions to ensure high levels of preventive attitudes.

Still, more interventions could be considered such as more affordable diagnostics and post-exposure male hygiene.

Researchers have yet to develop a vaccine for chancroid.


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